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KMID : 0816120060090010085
Korean Journal of Pediatric Gastroenterolology and Nutrition
2006 Volume.9 No. 1 p.85 ~ p.91
A Case of PFAPA Syndrome Mimicking Cyclie Vomiting Syndrome
Hong Seok-Pyo

Choi Byung-Kyu
Kim Yeo-Hyang
Choi Won-Joung
Kim Ae-Suk
Hwang Jin-Bok
Shin Hyun-Jung
Abstract
PFAPA syndrome is characterized by periodic fevers associated with aphthous stomatitis, pharyngitis, and cervical adenitis and is unusual in infants and children. We report on a case of PFAPA syndrome mimicking cyclic vomiting syndrome in a 42-month-old girl. She had experienced multiple episodes of cyclic vomiting with abdominal pain from age 20 to 30 months. When she was 30 months old, periodic fever with pharyngitis was combined with cyclic vomiting, and when 40 months old, aphthous stomatitis and cervical adenitis were added. These periodic symptoms and signs were not treated with prokinetics or antibiotics. Symptom duration of an episode was 3 days. After cimetidine therapy (150 mg three times daily for 6 months), her febrile and cyclic vomiting episodes ceased. At the time of writing she had not received therapy for 10 months and has remained well without periodic attack.
KEYWORD
PFAPA syndroe, Cyclic vomiting sydrome, periodic fever, Climetidine
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